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The spectrum of activities in this group is diverse, ranging from determining the sequence of biophysical events during exocytosis of secretory granules and elucidation of the function of the presynaptic Ca2+-sensing protein synaptotagmin-1 to the biophysical analysis of polymer interactions with biological nanopores. A particular long-term interest of the group is the development of novel technologies to facilitate both fundamental and applied research on biomembranes and membrane proteins.
Biomembrane Micro- and Nanotechnology
Using innovative microsystems we work to enhance the resolution and throughput of electrical recording from biomembranes. We construct biohybrid screening devices based on arrays of single biological nanopores in free-standing microbilayers, develop advanced methods of membrane protein reconstitution and also study the interaction of fluorescent semiconductor nanoparticles (quantum dots) with synthetic and biological membranes. More...
